Remote Ischemic Preconditioning

Remote Ischemic Preconditioning and Diabetic Macular Edema

Objective: Remote Ischemic Preconditioning (RIPC) as the transient ischemia and reperfusion of the arm is a promising method for protecting different tissue from future ischemia. These effects might be mediated through vascular and endothelial growth factor (VEGF) pathway. We investigated the influence of RIPC on diabetic macular edema (DME) as a chronic ischemic condition in patients who were ...

Remote Ischemic Preconditioning

Ischemic Preconditioning Ischemic preconditioning is a widely accepted concept, first introduced in 1986 by Murray et al,1 who showed in an animal experiment that multiple brief periods (5 min) of coronary artery occlusion dramatically reduced infarct size because of the subsequent sustained coronary occlusion. Numerous reports have followed and supported the concept. The mechanism of ischemic ...

Remote Ischemic Preconditioning and Cardiac Surgery.

To the Editor: Remote ischemic preconditioning (RIPC) is an inexpensive technique that is used to reduce perioperative organ damage. High-quality randomized trials have shown cardiac1 and renal2 protection with a possible reduction in mortality when RIPC was used in addition to halogenated agents.3 However, two recent multicenter, randomized trials, the Remote Ischemic Preconditioning for Heart...

Remote Ischemic Preconditioning for Cardiac Surgery

Remote Ischemic Preconditioning for Cardiac Surgery

Ever since its discovery more than 2 decades ago, remote ischemic preconditioning (RIPC) has generated tremendous interest among scientists and clinicians alike. However, two recent large, well-conducted, randomized controlled trials (RCTs) have failed to identify any significant benefit of RIPC during cardiac surgery. A reconciliatory yet objective review of cumulative evidence with regard to ...